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RNA silencing of CK1δ/ε reduces basal αENaC and Fxyd5 expression. A: mpkCCDc14 cells were treated with nontarget or CK1δ and ε siRNA for 48 h. Real-time PCR was used to evaluate changes in CK1δ (A), CK1ε (B), αENaC (C), or Fxyd5 (D) gene expression in CK1δ/ε siRNA-treated cells vs. nontarget. *P < 0.05, **P < 0.01; n = 6–8. Values are represented as means ± SE.
