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. 2012 Aug 23;303(8):G951–G960. doi: 10.1152/ajpgi.00158.2012

Fig. 3.

Fig. 3.

MLK3 modulates intestinal epithelial cell migration in vitro. A: MLK3 levels are higher in migrating (M) than confluent (C) human Caco-2 cells at 48 and 72 h (n = 6 per group). B: representative 24-h circular wounds of vehicle- and CEP-11004 (400 nM)-treated Caco-2 cells (top) and dose-dependent suppression of migration of Caco-2 cells (n = 15) by the MLK inhibitor CEP-11004 after 24 h (bottom). C: representative 6-h circular wounds of vehicle- and CEP-11004 (400 nM)-treated IEC-6 cells (top) and dose-dependent decrease in migration of rat IEC-6 cells (n = 15) by CEP-11004 after 6 h (bottom). *P < 0.05.