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. 2012 Aug 23;303(8):G951–G960. doi: 10.1152/ajpgi.00158.2012

Fig. 6.

Fig. 6.

Motogenic effect of MLK3 does not depend on cell proliferation or PTEN level. A: CEP-11004 does not change Caco-2 cell proliferation (n = 12). B: antimotogenic effects of CEP-11004 (CEP, 400 nM) are not reversed by hydroxyurea (OH-urea, n = 6). C: inhibition of ERK signaling increases PTEN level in Caco-2 cells (n = 6). D: loss of MLK signaling reduces cell migration in nontargeting (NT1) and PTEN small interfering RNA (siRNA)-treated Caco-2 cells (n = 15). Bars without a common letter (a, b, c, d) are significantly different at P < 0.01. *P < 0.05.