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Effect of ischemia and reperfusion on levels of PCr and ATP (A), the CK pseudo-first-order rate constant (kPCr→ATP), and rate of ATP synthesis via creatine kinase (CK flux; B) as well as Pi→ATP pseudo-first-order rate constant (kPi→ATP) and rate of ATP synthesis from Pi (C) in control (white) and CKM (gray) mouse hearts. Results are means ± SE for n = 5 in each group. *P < 0.01 vs. control (baseline); †P < 0.05 vs. CKM (baseline); #P < 0.01 vs. control (reflow).
