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VIP17/MAL overexpression alters morphology of cultured MDCK cysts. A: representative images of WT MDCK (top) and VIP17/MAL overexpressing MDCK (bottom) cysts, acquired by light microscopy, demonstrating more multilumen (arrows) cysts produced by cells overexpressing VIP17/MAL. B: quantitation of microscopic images revealing an increased incidence of multilumen cysts derived from VIP17/MAL overexpressing MDCK cells. **P < 0.01 (n = 100 cysts).
