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VIP17/MAL transgenic mice have abnormal cilia. Immunofluorescence analysis to detect cilia in control (CTL) and VIP17/MAL transgenic mice. Renal sections were labeled with antibody directed against the ciliary protein Arl13b (red) and the Na-K-ATPase (green). Control mice display readily detectable, long cilia protruding into the distal tubule lumen, while VIP17/MAL transgenic mice display fewer and smaller cilia within their dilated lumina/cysts. Scale bars (bottom right) are 10 μm.
