Skip to main content
. Author manuscript; available in PMC: 2013 Nov 1.
Published in final edited form as: Psychopharmacology (Berl). 2012 Aug 11;224(1):1–26. doi: 10.1007/s00213-012-2794-x

Fig. 4.

Fig. 4

Overlapping circuits for attachment and addiction. The VTA sends dopaminergic projections to the NAC, prefrontal cortex (PFC), and CP; these projections are all implicated in addiction, while only projections to NAC are implicated in attachment. The extended amygdala (E-Amg) is the presumptive source of AVP to the VP and LS in attachment, and CRF and glutamate to the NAC in addiction and attachment. The PVN is the source of OT release in the E-Amg and NAC. Glutamatergic projections link the PFC with the NAC, and GABAergic projections link the NAC and VP.