. Author manuscript; available in PMC: 2013 Nov 1.

Published in final edited form as: Cancer Causes Control. 2012 Sep 13;23(11):1839–1852. doi: 10.1007/s10552-012-0063-2

Table II.

Effect estimates for risk of ovarian cancer and ovarian cancer histologic subtypes in aspirin and non-aspirin NSAID users in the AARP study population

		All Cases (N=438) ^a				Serous (N=237) ^a				Mucinous (N=20) ^a				Endometrioid (N=31) ^a				Clear Cell (N=16) ^a				Other Epithelial (N=134) ^a
Use Type and Frequency		N ^b	Follow-Up (person-yr)	RR	95% CI	N ^b	Follow-Up (person-yr)	RR	95% CI	N ^b	Follow-Up (person-yr)	RR	95% CI	N ^b	Follow-Up (person-yr)	RR	95% CI	N ^b	Follow-Up (person-yr)	RR	95% CI	N ^b	Follow-Up (person-yr)	RR	95% CI
Aspirin
	Non-Regular Use ^c	283	1,359	ref	ref	155	781	ref	ref	11	45	ref	ref	19	84	ref	ref	10	37	ref	ref	88	411	ref	ref
	Regular Use ^d	150	683	1.06	0.87, 1.29	78	367	1.00	0.76, 1.32	8	46	1.57	0.63, 3.93	12	50	1.37	0.66, 2.84	6	36	1.36	0.49, 3.75	46	185	0.99	0.69, 1.42
Non-Aspirin NSAIDs
	Non-Regular Use ^c	319	1,510	ref	ref	172	845	ref	ref	16	80	ref	ref	23	102	ref	ref	14	67	ref	ref	94	415	ref	ref
	Regular Use ^d	111	489	0.93	0.74, 1.15	58	267	0.88	0.65, 1.19	4	12	0.69	0.23, 2.10	8	32	0.91	0.40, 2.06	2	6	0.38	0.09, 1.71	39	173	1.13	0.77, 1.65

^a.

Multivariate analysis adjusting for entry age, race/ethnicity, age of menarche, parity, age of (natural or surgical) menopause, hysterectomy status, PMH use, oral contraceptive use and first and second degree family history of ovarian cancer.

^b.

The number of non-regular and regular users in the aspirin and the other NSAIDs group do not add to the total number of cases because there are missing values in each.

^c.

Non-regular use was defined as taking less than one pill per week on average

^d.

Regular use was defined as taking one or more pills per week