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The diversification of mammalian Alp protein sequences. (A) The Alpi-related locus in five mammals showing Alp genes in yellow. Orthologs between mouse and rat shown in similar shades. (B) Maximum likelihood tree showing mammalian and bird Alp genes. In general, although the Alpi (Alp2) locus is orthologous and the flanking genes are orthologs among the various mammals, the tree shows that the Alpi-related genes themselves are usually not one-to-one orthologs.
