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The folding of R16m6(AB) has a greater dependence on solvent viscosity than does R16. Dependence of the relative folding and unfolding rate constants (k0/k) on relative solvent viscosity (η/η0). Values of kf determined at (a) ∆GD–N = 1.5 kcal mol− 1 and at (b) ∆GD–N = 0.0 kcal mol− 1, where kf = ku. The folding and unfolding of R16m6(AB), like R16o15c, has an intermediate dependence on solvent viscosity.
