Table 1.
Properties of classified units and connections used for CCG analysis from seven experiments.
| Desflurane concentration | ||||
|---|---|---|---|---|
| 0% | 2% | 4% | 6% | |
| ALL | ||||
| Units* | 434 | 309 | 346 | 271 |
| Spike rate, 1/s* | 5.5 (4.9, 6.5) | 4.2 (3.6, 4.8) | 3.3 (2.9, 3.7) | 2.8 (2.4, 3.2) |
| CLASSIFIED | ||||
| Connections, all* | 94 | 67 | 53 | 44 |
| Excitatory | 60 (64%) | 39 (58%) | 28 (53%) | 31 (71%) |
| Inhibitory | 34 (36%) | 28 (42%) | 25 (47%) | 13 (30%) |
| Putative cells, all | 90 | 47 | 50 | 42 |
| Pyramidal cell | 58 (64%) | 28 (60%) | 27 (54%) | 31 (74%) |
| Interneuron | 32 (36%) | 19 (40%) | 23 (46%) | 11 (26%) |
| Pyramidal spike rate, 1/s | 3.8 (3.3, 5.5)** | 3.5 (2.5, 6.2) | 3.5 (2.2, 3.9) | 2.6 (1.7, 3.4) |
| Interneuron spike rate, 1/s | 6.3 (4.9, 7.9) | 3.4 (1.6, 5.8) | 4.0 (2.5, 5.2) | 3.6 (1.4, 5.2) |
Number in parentheses indicates percent of all connections and cells. Spike rates are median with 95% confidence intervals. A significant linear decrease in the number of units and unclassified spike rates with desflurane was present. A significant difference in the spike rates of putative pyramidal cells and interneurons was observed at wakefulness.
*
p < 0.05, linear trend;
**
p < 0.05, Mann–Whitney.