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. Author manuscript; available in PMC: 2013 Oct 3.
Published in final edited form as: J Am Chem Soc. 2012 Sep 21;134(39):16430–16433. doi: 10.1021/ja307628w

Scheme 3. Reagents and Conditions.

Scheme 3

(a) 21, NIS, AgOTf, CH2Cl2, 3Å MS, 2 h; (b) BH3.THF, n-Bu2BOTf, CH2Cl2/THF, 0 °C, 3 h, 53% (over 2 steps) (c) 23, NIS, AgOTf, CH2Cl2, 3Å MS, −20 °C, 3 h, 78%; (d) HF/pyridine, THF, rt, 44 h, 58%; (e) 15, NIS, AgOTf, CH2Cl2, 3 Å MS, −20 °C, 36 h, 60%; (f) nano-Zn, AcOH, THF, rt, 20 min, 85%; (g) 15, NIS, AgOTf, CH2Cl2, 3 Å MS, −20 °C, 36 h, 50%.