Table 2. Cox multiple factors regression analyses for independent risk factors of the primary and secondary endpoints.

Variables	Primary endpoint			Secondary endpoint
	P	HR	95% CI	P	HR	95% CI
Age	0.034	1.040	1.003–1.078	0.031	1.028	1.003–1.054
Body mass index	0.506	0.981	0.926–1.039	1	1	0.970–1.030
Smoking	0.265	1.472	0.746–2.906	0.648	1.138	0.653–1.984
Drug type (ARB or ACEI)	0.037	2.124	1.048–4.306	0.137	1.454	0.888–2.380
Coronary heart disease	0.660	1.127	0.661–1.923	0.001	1.913	1.320–2.772
Diabetes mellitus	0.582	1.174	0.663–2.080	0.258	1.29	0.830–2.005
Cerebral infarction	0.006	2.239	1.257–3.988	0.778	0.928	0.552–1.560
Hyperlipidemia	0.233	0.560	0.216–1.453	0.156	0.599	0.295–1.215
Cardiac dysfunction	0.859	1.089	0.425–2.793	0.274	0.621	0.265–1.457
Renal dysfunction	0.035	1.423	1.025-1.976	0.416	0.837	0.545–1.286

ACEI: angiotensin II converting enzyme inhibitor; ARB: angiotensin receptor blocker.