Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Sep 26;32(39):13597–13607. doi: 10.1523/JNEUROSCI.1229-12.2012

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2012 the authors 0270-6474/12/3213597-11$15.00/0

PMC Copyright notice

Figure 2. — Blocking CB1 receptors increased AMPA mPSC frequency. A, Representative traces of mPSCs from an E10 motoneuron before (black trace) and after bath application of the CB1 inverse agonist AM 251 (5 μm; gray trace). B, Superimposed average traces of AMPA mPSC (left) and GABA mPSC (right) before (black trace) and after bath addition of AM 251 (gray trace). No change in mPSC kinetics was found in the presence of AM 251. C, Summary of the effect of AM 251 on mPSC frequencies. Only AMPA mPSC frequency increased significantly after AM 251 addition. *p < 0.01. D, Cumulative distribution plot showing the reduction of the IEI after AM 251 addition. E, Bar graph showing AM 251 had no effect on mPSC amplitudes.