Figure 4.

Growth inhibition activity of etoposide prodrug 6 in the presence and absence of catalytic antibody 38C2. The growth response of NXS2 neuroblastoma cells to a 72-h incubation with increasing concentrations of etoposide prodrug 6 in the presence and absence of 1 μM 38C2 catalytic antibody was analyzed by using a standard lactate dehydrogenase release assay. A serial dilution of etoposide and wells containing 1 μM 38C2 only are shown as controls. Data points and error bars represent mean values ± standard deviation.