Figure 2.

Hypoxia-induced expression of genes in the Rv3132/3133/3134 region of the MTB genome. (A) Composite of different portions of the MTB whole genome array, corresponding to genes in the region around Rv3133c. Shown are expression patterns after 2 h in ambient (Amb) or 0.2% O₂ (Hyp) as described in the text. Text above and below the figure indicates the gene number as defined by the H37Rv sequencing project (3). Red spots indicate an increase in mRNA level, green a decrease, and yellow no change. (B) Schematic representation of the genomic region around Rv3133c. Arrows denote the relative size, position, and transcriptional orientation of each gene.