Table 3. Inhibition potencies of the p27-KID mutants.
Variant | IC50 (nM) | 95% confidence intervals of IC50 (nM)a |
p27-KIDwt | 0.22 | 0.17–0.28 |
p27-KID+H | 4.1 | 3.3–5.1 |
p27-KID−H | 0.29 | 0.26–0.33 |
p27-KIDloop | 16.0 | 9.9–25.7 |
Error is reported as the 95% confidence interval of the IC50 from a curve fit of a triplicate data set.