Table 2. Amino acid substitutions of multiple genotypes in Taiwan.

genotype	Amino acid residue (of the gene)
	PB1							PB2	PA			HA							NP	NA									NB					M1	BM2			NS1				NS2
	38	66	357	390	391	457	652	555	485	530	617	63	123	165	180	196	244	493	534	42	107	126	187	249	296	341	464	466	13	45	67	82	84	105	21	59	108	110	114	119	179	87
TW08-I (2011–2012)	H	V	V	R	K	A	K	M	V	L	V	K	A	S	N	A	G	D	V	Q	I	T	K	V	R	D	D	A	P	D	S	M	I	K	M	N	S	N	Q	T	M	I
TW08-I *(2008)	.	.	.	.	.	T	.	.	.	S	.	.	.	.	.	T	.	.	.	.	T	.	.	V	S	.	.	.	.	N	P	V	.	.	.	S	.	.	.	.	.	V
TW08-II*	Y	I	I	K	R	T	R	L	I	S	I	R	P	I	Y	T	D	.	I	R	T	K	R	I	S	N	N	T	L	N	P	V	V	.	.	S	L	K	P	I	.	V
TW08-III*	.	.	.	.	.	T	.	.	.	S	.	R	P	.	.	T	S	E	.	.	T	.	.	I	S	.	.	.	.	N	P	V	.	R	V	S	L	.	P	.	I	V

^*Identical amino acids to those of TW08-1 (2011–2012) viruses were indicated by black dots.