Figure 8. Shh, Gli-1 and BMP-4 expression at 3-days post-STC throughout the bladder wall.

Low power views (Shh and Gli-1 at 50x, BMP-4 at 100x) confirm the transmural expression of these evolutionarily conserved signal modulators and their enhancement at 3-days post-op. All three signals were clearly noted in the urothelium (solid line), lamina and muscularis propria (dash line), as highlighted in the 400x insets.