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. 2012 Oct 12;7(10):e47158. doi: 10.1371/journal.pone.0047158

Table 3. The frequencies of the KDR −604T>C, 1192G>A, and 1719T>A polymorphisms between control subjects and patients with moyamoya disease.

Characteristics Controls (n = 243, %) Moyamoya patients (n = 107, %) AOR (95% CI) P *
KDR −604T>C
TT 113 (46.5) 47 (43.9) 1.000 (reference)
TC 108 (44.4) 50 (46.7) 1.131 (0.698–1.833) 0.617
CC 22 (9.1) 10 (9.3) 1.102 (0.482–2.517) 0.818
Dominant (CC vs. CA+AA) 1.128 (0.710–1.792) 0.609
Recessive (CC+CA vs. AA) 1.039 (0.470–2.296) 0.925
KDR 1192G>A
GG 186 (76.5) 80 (74.8) 1.000 (reference)
GA 52 (21.4) 22 (20.6) 0.994 (0.563–1.754) 0.983
AA 5 (2.1) 5 (4.7) 2.140 (0.596–7.693) 0.244
Dominant (GG vs. GA+AA) 1.101 (0.646–1.875) 0.725
Recessive (GG+GA vs. AA) 2.139 (0.597–7.665) 0.243
KDR 1719T>A
TT 46 (18.9) 26 (24.3) 1.000 (reference)
TA 114 (46.9) 45 (42.1) 0.764 (0.417–1.401) 0.384
AA 83 (34.2) 36 (33.6) 0.799 (0.427–1.495) 0.482
Dominant (TT vs. TA+AA) 0.775 (0.446–1.346) 0.365
Recessive (TT+TA vs. AA) 0.997 (0.613–1.620) 0.989
*

Adjusted by age and gender. AOR, adjusted odds ratio. CI, confidence interval.