Table 3. The frequencies of the KDR −604T>C, 1192G>A, and 1719T>A polymorphisms between control subjects and patients with moyamoya disease.
Characteristics | Controls (n = 243, %) | Moyamoya patients (n = 107, %) | AOR (95% CI) | P * |
KDR −604T>C | ||||
TT | 113 (46.5) | 47 (43.9) | 1.000 (reference) | |
TC | 108 (44.4) | 50 (46.7) | 1.131 (0.698–1.833) | 0.617 |
CC | 22 (9.1) | 10 (9.3) | 1.102 (0.482–2.517) | 0.818 |
Dominant (CC vs. CA+AA) | 1.128 (0.710–1.792) | 0.609 | ||
Recessive (CC+CA vs. AA) | 1.039 (0.470–2.296) | 0.925 | ||
KDR 1192G>A | ||||
GG | 186 (76.5) | 80 (74.8) | 1.000 (reference) | |
GA | 52 (21.4) | 22 (20.6) | 0.994 (0.563–1.754) | 0.983 |
AA | 5 (2.1) | 5 (4.7) | 2.140 (0.596–7.693) | 0.244 |
Dominant (GG vs. GA+AA) | 1.101 (0.646–1.875) | 0.725 | ||
Recessive (GG+GA vs. AA) | 2.139 (0.597–7.665) | 0.243 | ||
KDR 1719T>A | ||||
TT | 46 (18.9) | 26 (24.3) | 1.000 (reference) | |
TA | 114 (46.9) | 45 (42.1) | 0.764 (0.417–1.401) | 0.384 |
AA | 83 (34.2) | 36 (33.6) | 0.799 (0.427–1.495) | 0.482 |
Dominant (TT vs. TA+AA) | 0.775 (0.446–1.346) | 0.365 | ||
Recessive (TT+TA vs. AA) | 0.997 (0.613–1.620) | 0.989 |
Adjusted by age and gender. AOR, adjusted odds ratio. CI, confidence interval.