Fig. 3.

Effect of L-DOPA on dopaminergic cortical neurotransmission in stressed ENU2 mice. Recovery of DA and metabolite response to stress in mpFC of ENU2 mice submitted to 120 min of restraint following systemic administration of 0.5 mg/kg i.p. of L-DOPA. Dialysates were collected at 20-min intervals. Results are expressed as percent changes (means ± SE) from basal values. Statistical analyses were performed on raw data. Drug was administered to time 0. * P < 0.05 versus basal values. § P < 0.05 compared with vehicle-injected WT mice