Table 1.
Clinical pathologic characteristics in 872 subjects with and without Lewy bodies
| No Lewy bodies, n = 715 | Lewy body disease, n = 157 | P-value | |
|---|---|---|---|
| Age, in years* | 87.7 (6.4) | 88.8 (6.5) | 0.062 |
| Gender, female (n, %) | 469 (54) | 98 (11) | 0.45 |
| Education, years | 16.5 (3.6) | 16.2 (3.8) | 0.39 |
| Mini-mental state examination | 22.3 (8.5) | 17.8 (10.3) | <0.001 |
| Global cognition (summary score**) | −0.78 (1.12) | −1.31 (1.36) | <0.001 |
| Dementia, (n, %)*** | 267 (37) | 89 (57) | <0.001 |
| Interval last exam, months | 7.1 (4.4) | 7.0 (4.8) | 0.84 |
| Post-mortem interval, in hours | 8.5 (8.1) | 8.0 (7.8) | 0.43 |
| NIA-Reagan diagnosis of Alzheimer’s disease (pathological diagnosis) | 436 (61) | 103 (66) | 0.28 |
| Cerebral infarction (n, %) | 350 (49) | 73 (47) | 0.58 |
*Numbers are mean (SD), unless otherwise specified.
**See text for description of scores. ***See text for diagnostic criteria.