Skip to main content
. Author manuscript; available in PMC: 2013 Nov 16.
Published in final edited form as: Oncogene. 2012 Jul 9;32(20):2543–2554. doi: 10.1038/onc.2012.277

Figure 5.

Figure 5

p62/SQSTM1 cooperates with oncogenic PI3K to enhance cell proliferation in 3D culture. (A) Left: Phase timecourse of the indicated cell types in 3D culture. Right: Acinar size distribution of day 7 3D cultures of the indicated cell types. For each cell type, a total of 200 acini from three independent experiments were measured. Results represent mean ± SEM. *** p<0.001, Student's t test. Bar, 100μm. (B) Left: Day 7 acini derived from the indicated cell types were immunostained with antibodies against Ki67 (green), laminin-5 (red), and counterstained with DAPI (blue). Right: Percentage of Ki67 positive nuclei per acinus was quantified. For each cell type, a total of 150 acini from three independent experiments were counted. *** p<0.001, Student's t test. Bar, 50μm.