Table 2.

Laboratory data of parents with cryptic 21-hydroxylase deficiency.

	Cosyntropin stimulation						Early morning basal levels
Patient	17-OHPa (nmol/l)		Cortisol (nmol/l)		ACTH (pmol/l)	Androstene- dione (nmol/l)	Test. free (pmol/l)	Test. total (nmol/l)	DHEA (nmol/l)	DHEAS (µmol/l)	Plasma renin activity (µg/l per hour)	Epinephrine (pmol/l)	Metanephrine (pmol/l)
	Basal	60 min	Basal	60 min
2	22.7	125	395	497b	5.3	6.0	10	1.1	27.1	4.4	2.4	49	161
3	14.8	56	497	582	3.3	2.8	4	0.5	4.2	<0.4	2.9	44	120
4	15.1	132	312	582	3.2	3.9	24	1.0	34c	3.4	1.1	55	120
5	49.2	211	417	566	8.1	13.0c	56	2.5		7.6c	1.2	251	146
6	13.7	157	246b	574	5.0	6.6	316c	2.0	16.3	4.1	1.2	60
7	6.3	110	160b	370b	1.7	3.9	21	1.1		2.7	0.7	142	120
9	12.3	117	259b	491b	6.4	4.5	552	22.1	10.8	4.4c	0.6	262	244
10	81.0	363	403	676	5.8	10.5c	2290c	15.3		3.3	1.7

^aTo convert from SI units to metric: 17-OHP×33.1 ng/dl; cortisol×0.0362 g/dl; ACTH×4.54 pg/ml; androstenedione×28.65 ng/dl; free testosterone×0.288 pg/ml; testosterone×28.82 ng/dl; DHEA×28.82 ng/dl; DHEA-S×36.9 g/dl; epinephrine×0.183 pg/ml; and metanephrine 0.192 pg/ml.

^bSub-normal cortisol level defined as 60-min stimulated cortisol=500 nmol/l (21, 22).

^cElevated for age and sex.