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. Author manuscript; available in PMC: 2012 Oct 15.
Published in final edited form as: Methods. 2009 Aug 3;49(2):148–166. doi: 10.1016/j.ymeth.2009.07.005

Figure 19.

Figure 19

The RNA component of RNase P. (A) Secondary structure of E. coli P RNA. (B) Transition state model for the reaction catalyzed by RNase P. Question marks denote putative metal ion-ligand interactions awaiting experimental verification. [Adapted from (175), with permission.] (C) Crystal structure of the P RNA from B. stearothermophilus at 3.3 Å (PDB file 2A64). (D) Location (in red) of the P4 helix within the B. stearothermophilus P RNA.