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Plasmodium falciparum infection in a girl heterozygous for Glucose-6-phosphate dehydrogenase (G6PD) deficiency. The blood film was stained by a procedure that causes lysis of G6PD-deficient red cells, producing their ghost-like appearance. As G6PD deficiency heterozygosity is a somatic cell mosaic as a result of X chromosome inactivation it was possible to show by this procedure that P. falciparum parasitized red cells are predominantly G6PD normal (see Luzzatto et al, 1969).
