TABLE IV.
Branched DNA (bDNA) Analysis of Human CASMC Gene Expression After 7 Days of DM, Calcitriol + DM or Paricalcitol + DM Exposure
| Fold change | ||
|---|---|---|
| Gene | Cal + DM vs. DM | Par + DM vs. DM |
| Alkaline phosphatase (ALP) | 1.47 | 1.31 |
| Matrix gla protein (MGP) | 1.08 | −1.10 |
| Fibrillin 1 (FBN1) | 1.04 | 1.08 |
| Osteoprotegerin (TNFRSF11B) | 2.13 | 1.82 |
| Secreted frizzled related protein-3 (FRZB) | −1.25 | −1.08 |
| Ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) | −1.52 | −1.40 |
| Runt related transcription factor 2 (RUNX2) | 1.04 | −1.09 |
Cal, calcitriol; Par, paricalcitol; DM, differentiation medium.
The data were normalized to cyclophilin levels and then were transformed using log2.
The values displayed here are fold change (or negative reciprocal if fc < 1) of the treatment 1–treatment 2, where treatments 1 and 2 are given as column names.
Bold values indicate fold changes are not equal to 1 (P < 0.05).