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Clinical features of the patients. A: Case1. Generalized lack of subcutaneous fat, marked muscular hypertrophy, hollow cheeks, and broad hands. B–D: Case2. Complete lipodystrophy (B and D), muscular hypertrophy (B), protuberant abdomen and hepatosplenomegaly (black mark for liver border) (B), enlarged hands (B) unusual facial features (B) and crassitude of the penis (B&C).
