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. Author manuscript; available in PMC: 2012 Oct 15.
Published in final edited form as: Gene Ther. 2010 Aug 19;17(12):1476–1483. doi: 10.1038/gt.2010.110

Figure 2. Myogenic regeneration in young and old mdx mice.

Figure 2

Tissue sections were immunostained for embryonic myosin heavy chain (eMyHC) expression (red), to assay levels of muscle regeneration. The first panel from the left represents tissues from negative control mdx mice treated with PBS. The next two panels represent the tissues treated by AAV2-IKKα-dn and AAV2-IKKα-wt. Finally, the last two panels represent the tissues treated by AAV2-IKKβ-dn and AAV2-IKKβ-wt. (A) At 1 month post -treatment, gastrocnemius (GAS) muscles were isolated from AAV vector-treated young mdx mice at 1 and 2 months of age. (B) GAS and tibialis anterior (TA) muscle tissues of old mdx mice, treated at 11 months of age, were collected at 1 month post-treatment. All panels are shown at 100x magnification.