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. Author manuscript; available in PMC: 2012 Oct 15.
Published in final edited form as: Nat Struct Mol Biol. 2010 Dec 5;18(1):75–79. doi: 10.1038/nsmb.1942

Figure 2.

Figure 2

CtIP knock-down alters end-joining during CSR. (a) Sµ-Sα junctions from CIT-stimulated CH12 cells infected with control or CtIP-1 shRNA were analyzed. Sequence data was compiled from six independent experiments. (b) The spectrum of junctions in control versus CtIP knock-down cells was tabulated. The difference in the percentage of junctions with microhomology of 4 nucleotides or more was statistically significant (p=0.02). (c) Sµ-Sα junctions in CtIP knock-down cells transduced with empty vector or vector encoding hsCtIP were analyzed.