TABLE 3.
Associations between exclusive breastfeeding and mortality within strata of potential effect modifiers
| Child mortality (0–60 mo of age) |
||||
| Potential modifier | n | RR (95% CI)1 | P1 | P-interaction2 |
| Time-varying child HIV status | ||||
| Negative | 28 | 0.62 (0.43, 0.91) | 0.01 | 0.06 |
| Positive | 106 | 0.95 (0.79, 1.15) | 0.63 | — |
| Maternal baseline CD4+ cell count | ||||
| <350 cells/μL | 63 | 0.82 (0.64, 1.05) | 0.12 | 0.31 |
| ≥350 cells/μL | 61 | 0.97 (0.75, 1.26) | 0.84 | — |
| Maternal baseline CD8+ cell count | ||||
| <565 cells/μL | 39 | 1.20 (0.85, 1.71) | 0.30 | 0.06 |
| ≥565 cells/μL | 85 | 0.80 (0.63, 1.00) | 0.05 | — |
| Maternal baseline lymphocyte count | ||||
| <1340 lymphocytes/μL | 37 | 1.05 (0.72, 1.55) | 0.79 | 0.27 |
| ≥1340 lymphocytes/μL | 94 | 0.83 (0.68, 1.03) | 0.08 | — |
1
Values were obtained by using adjusted Cox proportional hazards regression models. Covariates were adjusted as indicated in Table 2.
2
P values for interaction between exclusive breastfeeding and potential modifiers were obtained by using likelihood-ratio tests.