TABLE 2.
Within-group changes |
|||
VLCD (n = 3773) | LCD (n = 4588) | Restricted normal-food diet (n = 676) | |
Intention to treat (n = 9037)2 | |||
Body weight (kg) | −11.5 (−11.7, −11.2) | −6.8 (−7.0, −6.6) | −5.0 (−5.6, −4.5) |
Body weight (%) | −11.7 (−11.9, −11.4) | −7.7 (−7.9, −7.5) | −6.0 (−6.5, −5.4) |
Waist circumference (cm) | −8.6 (−8.9, −8.3) | −5.9 (−6.1, −5.6) | −4.5 (−5.2, −3.9) |
Completers only (n = 7109) | |||
Body weight (kg) | −13.8 (−14.0, −13.5) | −8.9 (−9.2, −8.7) | −7.0 (−7.6, −6.4) |
Body weight (%) | −14.0 (−14.2, −13.8) | −10.1 (−10.4, −9.9) | −8.3 (−8.9, −7.7) |
Waist circumference (cm) | −14.4 (−14.8, −14.1) | −10.1 (−10.4, −9.8) | −8.3 (−9.1, −7.5) |
All values are estimated marginal means; 95% CIs in parentheses. ANCOVA was conducted, and the values were adjusted for age, sex, center, calendar year, history of cardiovascular disease and cancer during the past 5 y, and dispensation of drugs for obesity, diabetes, hypertension, dyslipidemia, depression, and psychosis during the 6 mo preceding baseline. LCD, low-calorie diet; VLCD, very-low-calorie diet.
With baseline substitution.