Schematic of the study protocol. Participants (n = 23) underwent a fasting fMRI scanning session beginning at 0830 h followed by a standardized breakfast with 20% of their estimated daily caloric needs. Each participant was randomly assigned to a second fMRI session time (15, 30, 60, 120, 180, 240, or 300 min after the start of their standardized breakfast) to vary satiety across participants. Immediately after the second fMRI scanning session, participants were presented with an ad libitum buffet. Participants completed serial visual analog scale appetite ratings; appeal ratings followed each fMRI scanning session.