Table IV. Serum concentrations of 13 cytokines (pg/ml) evaluated by multiplexed immunoassay in normal pregnant women, pregnant women with acute pyelonephritis and patients with preeclampsia.

	Normal pregnancy (n = 31)	Acute pyelonephritis (n=31)	p
GA at blood sampling (weeks)	31.4 (26.3-36.1)	31.9 (26.7-36.4)	0.9
IL-1β	0.7 (0.3-3.4)	0.9 (0.3-2.9)	0.9
IL-2	2.3 (0.5-4.3)	2.1 (0.1-4.7)	0.9
IL-4	7.4 (0-32.3)	3.7 (0.5-24.9)	0.8
IL-5	0 (0-0.7)	0.1 (0-0.9)	0.8
IL-6	3.5 (1.6-11.8)	40.0 (22.6-117.5)	<0.001*
IL-7	3.8 (2.8-5.2)	6.3 (4.3-9.8)	0.004*
IL-8	2.5 (1.9-4.3)	9.2 (4.9-18.9)	<0.001*
IL-10	3.5 (2.5-7.1)	20.3 (7.9-53.8)	<0.001*
IL-12p70	0.3 (0-2.6)	0.5 (0-1.7)	0.8
IL-13	0 (0-2.7)	0.3 (0-3.9)	0.3
IFN-γ	0 (0-6.5)	7.7 (3.3-14.3)	0.001*
GM-CSF	0.9 (0-3.3)	1.1 (0.3-2.6)	0.7
TNF-α	2.5 (1.7-2.8)	5.3 (4.1-9.3)	<0.001*

Values expressed as median (inter-quartile range);

^*p<0.05