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Uneven expansion of the budding yeast nucleus. In wild type budding yeast, the nucleolus (in red) forms a crescent shaped structure apposing the NE (in green) that caps the chromatin (in blue). In spo7Δ, nem1Δ, or pah1Δ mutant cells, the NE expands only in the region that is adjacent to the nucleolus, forming a “flare”, while the NE adjacent to the chromatin retains it original shape.
