Table 1.

Physiological variables

Physiological variables	Conscious		α-Chloralose anesthesia
	Saline control	l-NAME	Saline control	l-NAME
Before measurement of CBF	n = 6	n = 6	n = 7	n = 6
Mean arterial blood pressure, mmHg	118  ± 2	152  ± 2**	114  ± 5	141  ± 3†
Paco2, mmHg	34  ± 1	32  ± 1	32  ± 1	33  ± 1
Pao2, mmHg	89  ± 3	93  ± 2	138  ± 6**	128  ± 9
Arterial pH	7.45  ± 0.01	7.45  ± 0.01	7.49  ± 0.01**	7.48  ± 0.01
Plasma glucose, mM	7.6  ± 0.3	6.9  ± 0.2	6.5  ± 0.3	5.7  ± 0.3
Before measurement of cerebral glucose utilization	n = 6	n = 6	n = 5	n = 5
Mean arterial blood pressure, mmHg	121  ± 4	158  ± 4**	121  ± 4	140  ± 6†
Paco2, mmHg	36  ± 1	36  ± 1	33  ± 1	34  ± 1
Pao2, mmHg	90  ± 3	95  ± 2	128  ± 8**	111  ± 10
Arterial pH	7.44  ± 0.01	7.44  ± 0.01	7.48  ± 0.01**	7.45  ± 0.01
Plasma glucose, mM	7.1  ± 0.4	6.2  ± 0.1	6.2  ± 0.1	5.8  ± 0.3

Values are means ± SEM of number of animals in parentheses.  

^*, P < 0.05;  

^**, P < 0.01;  

^**, P < 0.001 compared to the conscious saline controls.  

^†, P < 0.001 compared to the α-chloralose-anesthetized saline-treated groups.