Figure 1.

Results of computing the perturbations of 20 Netpath pathways in 18 human cancers. Each point represents a pathway-cancer pair: the x-axis is the p-value of the most-perturbed sub-pathway and the y-axis is the p-value of the entire pathway in the cancer, with smaller p-values indicating greater perturbation. The x = y line is shown in dashed green. (a) Data for all pathway-cancer pairs. (b) Data restricted to pathway-cancer pairs where the most perturbed sub-pathway has a p-value at most 0.01.