Table 1.
Fraction of interactions in a pathway that occur in any significant most-perturbed sub-pathway
| Pathway | #cancers perturbed in | #measured interactions | #perturbed interactions | %perturbed interactions |
|---|---|---|---|---|
| Alpha6 Beta4 Integrin | 14 | 32 | 24 | 75 |
| B Cell Receptor | 13 | 105 | 79 | 75.2 |
| EGFR1 | 16 | 78 | 45 | 57.7 |
| ID | 1 | 53 | 15 | 28.3 |
| IL-2 | 17 | 75 | 53 | 70.7 |
| IL-3 | 18 | 58 | 38 | 65.5 |
| IL-4 | 11 | 36 | 25 | 69.4 |
| IL-6 | 3 | 46 | 23 | 50 |
| IL-7 | 4 | 20 | 12 | 60.0 |
| Kit Receptor | 12 | 55 | 29 | 52.7 |
| T Cell Receptor | 12 | 102 | 67 | 65.7 |
| TGF-beta Receptor | 15 | 155 | 87 | 56.1 |
| TNF-alpha | 17 | 109 | 82 | 75.2 |
The third column contains the number of interactions that connect genes that are also present in the gene expression data.