Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Jul 27;21(21):4680–4702. doi: 10.1093/hmg/dds309

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author 2012. Published by Oxford University Press

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 1. — Mitochondrial deficits are related with an altered ETC complex I activity. (A) Immunoblot for mitochondrial markers (Hsp60, VDAC/Porin, TOM20, COXIV) from CT and sPD cybrids. (B) Densitometric analysis of mitochondrial marker levels (n= 8, *P< 0.05, versus CT cybrids). (C) Mitochondrial respiratory chain complex I activity. Data are reported in nmol/min/mg as the mean ± SEM (n= 12; **P< 0.01, versus CT cybrids). (D) TOM20 immunostaining (green) of CT and sPD cybrids showing alterations in mitochondria distribution, elongation and interconnectivity in sPD cybrids. Hoechst 33342- stained nuclei are in blue (n= 3, ***P< 0.001, mitochondrial elongation sPD versus CT cybrids; *P< 0.05, mitochondrial interconnectivity sPD versus CT cybrids). Scale bar: 20 µm.