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Dentatin induces apoptosis in prostate cancer cell lines. (a) PC-3 and LNCaP cells were treated with 15 μM of dentation for 24 hours. Cells were stained with Hoechst 33342 for nucleus and Annexin V-FITC to detect apoptotic cells. (b) Fluorescence intensity of Annexin V in PC-3 or LNCaP cells treated with designated concentration of dentatin. Data were shown as mean ± SD. Significant differences (*P < 0.05) between dentatin-treated and untreated control cells.
