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Dentatin decreases pro-survival molecules of prostate cancer cells. PC-3 and LNCaP were treated with control DMSO, control drug paclitaxel or dentatin. Cell lysates collected were resolved with SDS-PAGE gel, blotted onto membrane, and probed with antibodies against pro-survival molecules Bcl-2, Bcl-xL and Survivin. The membranes were stripped and reprobed with antibody to β-actin as loading control.
