Figure 7.
Quantal events at corticostriatal and thalamostriatal synapses. Sample traces of mEPSCs recorded after cortical (A, CTX) and thalamic (B, Th) stimulation. Traces were recorded in the voltage-clamp configuration, in the presence of 2 mm Ca2+ or 2 mm Sr2+/0 Ca2+ in the external bathing solution, from hWT and hMT1 mice. Holding potential: −60 mV. A1, B1, The plots show no significant change in asynchronous release frequency in the three genotypes following cortical (A1) and thalamic (B1) stimulation.