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. Author manuscript; available in PMC: 2012 Oct 15.
Published in final edited form as: Gut. 2011 Dec 16;61(10):1398–1409. doi: 10.1136/gutjnl-2011-300539

Figure 4.

Figure 4

mRNA levels of antral gastrin (Ai) and fundic cholecystokinin B (CCKB) receptor (Aiii) and histamine H2 receptor (Aiv) were measured following IL-11 or saline treatment by quantitative PCR, standardised against rL32 and expressed as fold change compared with controls (ΔΔCt method). G cells (Aii) were localised in control mice and treatment groups. Stained cells/mm were quantified. Gastric content pH was measured from wild-type (WT) mice treated with IL-11 or saline (B). Electron microscopic analysis of parietal cells from saline (Ci–ii) or IL-11-treated mice (Ciii–iv). Gastric acid secretion (D) was measured at 15 min intervals in mice treated with (i) IL-11, (ii) histamine, (ii) histamine plus IL-11, 15 min later (iii) IL-11 plus histamine 15 min later. Acid secretion was expressed as percentage change from baseline. Bars refer to mean±SEM; *p≤0.05.