Table 3. Respiratory and systemic symptoms associated with KIPyV or WUPyV detection within the prior week or month in HCT recipients*.
| Symptom | KIPyV† |
WUPyV† |
|||
|---|---|---|---|---|---|
| OR (95% CI) | p value | OR (95% CI) | p value | ||
| Within prior week | |||||
| Runny nose | 1.3 (0.7–2.4) | 0.39 | 1.2 (0.5–3.2) | 0.66 | |
| Sinus congestion | 0.8 (0.5–1.3) | 0.34 | 1.4 (0.6–3.5) | 0.46 | |
| Postnasal drip | 0.8 (0.4–1.8) | 0.65 | 1.2 (0.5–3.0) | 0.72 | |
| Shortness of breath | 0.9 (0.4–1.8) | 0.73 | 0.9 (0.3–2.9) | 0.83 | |
| Sputum production | 1.7 (1.0–2.9) | 0.04 | 1.5 (0.5–4.8) | 0.47 | |
| Pharyngitis | 1.0 (0.6–1.7) | 0.99 | 2.1 (0.8–5.4) | 0.12 | |
| Sneezing | 1.2 (0.7–2.0) | 0.54 | 1.3 (0.6–2.9) | 0.48 | |
| Watery eyes | 1.5 (0.8–2.6) | 0.17 | 1.6 (0.4–6.2) | 0.51 | |
| Cough | 1.1 (0.6–2.0) | 0.68 | 1.4 (0.6–3.5) | 0.47 | |
| Wheezing | 1.1 (0.5–2.5) | 0.82 | 2.1 (0.8–5.9) | 0.15 | |
| Fever | 0.9 (0.5–1.5) | 0.59 | 1.3 (0.4–3.7) | 0.64 | |
| Headache | 0.6 (0.4–1.1) | 0.08 | 0.7 (0.2–2.8) | 0.58 | |
| Myalgia | 0.6 (0.3–1.1) | 0.08 | 1.1 (0.3–3.5) | 0.92 | |
| Diarrhea | 0.8 (0.5–1.3) | 0.40 | 0.7 (0.3–1.8) | 0.47 | |
| Within prior month | |||||
| Cough | 1.0 (0.6–1.8) | 0.91 | 1.6 (0.7–3.5) | 0.26 | |
| Wheezing | 1.0 (0.5–2.2) | 0.99 | 3.1 (1.2–8.1) | 0.02 | |
*Values are for 211 of 222 patients with symptom survey data. Ear pain was too rare for analysis. KIPyV, KI polyomavirus; WUPyV, WU polyomavirus; HCT, hematopoietic cell transplantation; OR, odds ratio. †Each result was adjusted for the following covariates: detection of the other polyomavirus (KIPyV or WUPyV), detection of a respiratory virus, day relative to transplantation, age at transplantation, stem cell source, donor type, and grades 2–4 acute graft-versus-host-disease.