TABLE 2.
Median and 10th to 90th Percentiles of Organ Doses (Gy) Among Women Irradiated for Benign Gynecologic Disorders, by Modality of Radiotherapy
| Organ dose (Gy) |
||||||||
|---|---|---|---|---|---|---|---|---|
| Modality of RT |
||||||||
| Any RTa |
X ray |
Brachytherapy |
Both |
|||||
| Organ | Median | P10–P90b | Median | P10–P90b | Median | P10–P90b | Median | P10–P90b |
| Uterus | 38 | 8–58 | 7.1 | 4.4–11 | 43 | 19–58 | 41 | 35–61 |
| Uterine cervix | 120 | 8–180 | 7.1 | 4.4–11 | 130 | 59–180 | 120 | 98–180 |
| Uterine corpus | 34 | 7–50 | 7.1 | 4.4–11 | 38 | 17–50 | 37 | 31–53 |
| Bladderc | 7.2 | 4.7–12 | 6.5 | 3.8–10 | 7.2 | 4.0–9.6 | 9.1 | 8.3–15 |
| Rectumd | 4.8 | 2.4–9.0 | 7.2 | 4.2–11 | 3.6 | 2.0–4.8 | 6.1 | 5.7–12 |
| Ovary | 3.1 | 1.6–8.1 | 7.1 | 4.4–11 | 2.8 | 1.2–3.7 | 5.5 | 4.5–9.4 |
| Colon (entire)e | 1.7 | 0.8–4.4 | 3.9 | 2.5–7.4 | 1.5 | 0.7–2.0 | 3.0 | 2.4–5.1 |
| Sigmoid colon | 3.8 | 1.9–7.9 | 7.0 | 4.4–10 | 3.4 | 1.5–4.6 | 5.7 | 4.8–9.6 |
| Liver | 0.2 | 0.1–0.9 | 0.7 | 0.3–1.2 | 0.2 | 0.1–0.3 | 0.5 | 0.5–1.2 |
| Stomach | 0.3 | 0.1–0.9 | 0.8 | 0.4–1.4 | 0.3 | 0.1–0.3 | 0.6 | 0.5–1.1 |
| Kidney | 0.3 | 0.1–1.1 | 1.0 | 0.4–1.6 | 0.2 | 0.1–0.3 | 0.7 | 0.5–1.3 |
| Pancreas | 0.2 | 0.1–1.1 | 1.1 | 0.5–1.7 | 0.2 | 0.1–0.3 | 0.7 | 0.5–1.3 |
| Lung | 0.05 | 0.0–0.1 | 0.1 | 0.0–0.1 | 0.04 | 0.0–0.1 | 0.1 | 0.1–0.1 |
| Breast | 0.04 | 0.0–0.1 | 0.1 | 0.0–0.1 | 0.04 | 0.0–0.1 | 0.1 | 0.1–0.1 |
| Thyroid | 0.01 | 0.0–0.0 | 0.01 | 0.0–0.0 | 0.01 | 0.0–0.0 | 0.02 | 0.0–0.0 |
| Brain | 0.004 | 0.0–0.0 | 0.004 | 0.0–0.0 | 0.004 | 0.0–0.0 | 0.005 | 0.0–0.0 |
| Total active bone marrowf | 0.7 | 0.4–2.0 | 3.3 | 1.1–3.3 | 0.6 | 0.3–0.9 | 1.6 | 1.2–2.8 |
Radiotherapy.
10th and 90th percentiles of the dose.
Average bladder dose among women who received brachytherapy was assumed to equal 4.0 Gy/1000 mg · h (range within bladder = 1.0 to 15.0 Gy/1000 mg · h).
Average dose to rectum among women who received brachytherapy was assumed to equal 2.0 Gy/1000 mg · h (range within rectum = 0.9 to 5.5 Gy/1000 mg · h).
An average dose for entire colon was calculated by first averaging estimates for 2 subsites of the ascending and descending colon, respectively, and then taking an equally weighted average of doses to the ascending, descending, transverse and sigmoid segments.
The dose to the total active bone marrow was a weighted average of the dose to each of 14 anatomic compartments, with weights given by the presumed percentage contributions of each compartment to the total active bone Marrow (Cristy 1981).