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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Radiat Res. 2012 Aug 2;178(4):266–279. doi: 10.1667/rr2845.1

Relative Risks of Mortality Due to Selected Cancers by Modality of Treatment

X ray Brachytherapy Both
Cause of death na RRb 95% CIc na RRb 95% CIc na RRb 95% CIc
Number of women: 1,947 5,981 1,841
Person-years: 59,096 175,086 54,408
All causes 1,342 1.1 1.0–1.2 4,391 1.1 1.1–1.2 1,429 1.1 1.0–1.1
All solid cancers 253 1.3 1.1–1.5 853 1.3 1.2–1.5 289 1.4 1.2–1.6
Heavily-irradiated sites (>1 Gy) 125 1.9 1.5–2.5 410 1.9 1.5–2.3 155 2.0 1.6–2.6
 Uterine cervix 12 1.3 0.6–2.9 35 1.1 0.6–2.1 18 1.4 0.7–3.0
 Uterine corpus 30 3.2 1.8–6.1 129 3.7 2.2–6.6 58 4.1 2.4–7.6
 Bladder 9 3.3 1.1–10.7 32 3.5 1.5–10.2 7 2.1 0.7–7.3
 Rectum 10 4.3 1.4–15.6 27 3.7 1.4–12.6 14 5.9 2.0–21.3
 Ovary 24 2.1 1.1–3.7 53 1.5 0.9–2.6 28 2.6 1.4–4.7
 Other genital organs 1 0.3 0.0–1.8 5 0.5 0.1–1.6 4 1.2 0.3–4.5
 Colon 40 1.4 0.9–2.2 134 1.5 1.1–2.2 30 1.1 0.7–1.7
Lightly-irradiated sites (0.1–1 Gy)
 Liver, gallbladder and bile ducts 4 0.5 0.1–1.4 23 0.9 0.4–1.7 15 1.6 0.7–3.4
 Stomach 13 1.1 0.6–2.3 40 1.0 0.6–1.8 15 1.0 0.5–2.1
 Kidney 6 1.1 0.4–3.2 13 0.7 0.3–1.8 5 0.8 0.2–2.4
 Pancreas 10 0.8 0.3–1.5 52 1.3 0.8–2.2 12 1.1 0.5–2.1
Very lightly-irradiated sites
(<0.1 Gy)
 Lung 20 1.1 0.6–1.8 49 1.0 0.7–1.6 15 1.2 0.6–2.3
 Breast 39 0.9 0.6–1.4 127 1.0 0.8–1.4 28 0.7 0.5–1.2
 Esophagus 0 0.0 d 6 e 4 e
 Thyroid 1 0.8 0.0–8.7 2 0.5 0.1–4.5 2 1.5 0.2–14.6
 Buccal cavity and pharynx 3 1.3 0.3–6.0 6 0.8 0.2–3.4 2 0.9 0.1–4.9
 Brain 4 e 13 e 3 e
Bone and connective tissue cancers
 Bone 4 e 0 0.0 —d 0 0.0 —d
 Connective tissues 1 e 2 e 3 e
Lymphatic/Hematopoietic
 cancers
 Non-Hodgkin lymphoma 11 1.0 0.5–2.1 29 0.9 0.5–1.6 8 0.8 0.3–1.8
 Hodgkin lymphoma 2 0.8 0.1–4.1 7 0.9 0.3–3.4 0 0.0–
 Multiple myeloma 4 0.9 0.3–3.0 10 0.8 0.3–2.1 4 1.1 0.3–3.4
 Leukemia 9 1.6 0.6–3.9 47 2.6 1.4–5.5 14 2.4 1.1–5.6
 Non-CLLf leukemia 5 e 35 e 11 e
 Myeloid leukemia 3 e 19 e 6 e
 Lymphocytic leukemia 4 1.0 0.3–3.5 12 0.9 0.4–2.4 3 0.7 0.2–2.7
a

Number of deaths.

b

Relative risk.

c

95% confidence interval (relative risks and 95% confidence intervals for Lymphatic/Hematopoietic cancers were calculated based on standardized mortality rate regression).

d

Not applicable.

e

Relative risk and 95% confidence intervals were not presented due to small number of deaths among no RT group.

f

Chronic lymphocytic leukemia.