Skip to main content
. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Ann Biomed Eng. 2012 Aug 23;40(11):2379–2398. doi: 10.1007/s10439-012-0613-5

Figure 5.

Figure 5

Schematic diagram of the physiochemical processes that influence the simultaneous blood-tissue exchange of O2 and CO2. CA is carbonic anhydrase, the enzyme accelerating the CO2 hydration reaction inside the RBCs and tissue. The HCO3−/Cl− exchange between plasma and RBCs occurs through the band-3 anion channels on the membrane of RBCs, satisfying the Gibbs-Donnan electrochemical equilibrium principle. [Figure from Geers54]