FIGURE 4.
Mitochondrial localization of NMDA receptor. Post-embedding immunogold labeling of NR2a and electron microscopy revealed gold particles overlying mitochondria in a pellet (A) and in situ (B). Scale bars = 500 nm. C, OMM fractions were selectively labeled with an antibody directed against the voltage-dependent anion channel (VDAC), and IMM fractions were selectively labeled with an antibody against the adenine nucleotide translocator (ANT). Note that both NR1 and NR2a were confined to the IMM.