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. 2012 Oct 15;7(10):e47558. doi: 10.1371/journal.pone.0047558

Figure 1. Effect of downregulation of endogenous lamin A/C on chromatin markers.

Figure 1

(A) HeLa cells transiently expressing control shRNA or lamin A/C shRNA vectors (co-expressing GFP) were immunostained with the indicated antibodies. Arrows indicate cells showing depletion of HP1α, HP1β or lamin A/C. (B) Western blots of lysates (∼50,000 cells) from stable clones of control shRNA or lamin A/C shRNA (Cl 27) were probed with the indicated antibodies. The results shown are representative of three independent experiments. Bar, 10 µm.