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Gross phenotype of K5-COX-2 transgenic and wt mice. Hind foot of a 7-week-old wt (A) and a transgenic mouse (B) with long nails. (C) Hair coat in the transgenic neonatal (tr) 8 days after birth, showing an almost naked appearance compared with a wt control. (D–F) Twelve-week-old wt (D) and moderately (E) and severely (F) affected transgenic mice, the latter with much less hair especially on back skin. Hair, particularly of the neck, looked greasy.
